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2059148-82-0 br Statistical analysis br All values are expre
2020-08-30
2.11. Statistical analysis All values are expressed as the mean ± standard deviation (SD). GraphPad Prism 5.0 was used for the analysis of the experimental data. Statistical analysis of the data was performed using the T-test or the One-Way ANOVA-Ordinary test. A P value of less than 0.05 was c
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br Stiffening and aligned extracellular matrices are observe
2020-08-30
Stiffening and aligned extracellular matrices are observed in the vicinity of tumors. Collagen fibers near the tumor tend to be aligned, and cancer 13095-48-2 reorganize collagen fibers to be aligned. This collagen alignment contributes the tumor progression [12,13]. It has been reported that the
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br Contents lists available at ScienceDirect br Phytomedicin
2020-08-30
Contents lists available at ScienceDirect Phytomedicine journal homepage: www.elsevier.com/locate/phymed Original Article Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly T targeting the TOPK signaling pathway in colon cancer Ran Zhaoa,b,1, Hai Huanga,1, Bu Y
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br Apoptosis induction assay br Apoptosis
2020-08-30
2.15. Apoptosis induction assay Apoptosis was measured using Annexin V-Cy5 (Biovision Inc., CA, USA) and 7-aminoactinomycin D (7-AAD) (AAT Bioquest, CA USA) [24,25]. 20,000 cells were seeded into 48-well plates and allowed to adhere for 24 h at 37 °C in a 5% CO2 and 95% air humidified incubator
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Calcium carbonate CaCO recognized as a naturally biomineral
2020-08-28
Calcium carbonate (CaCO3), recognized as a naturally biomineral, is highly desirable for biomedical applications due to excellent bio-compatibility and biodegradability. Other merits like low price and ease of mass production also make CaCO3 suitable in the delivery of drugs, genes or other biomo
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br In this study we
2020-08-28
In this study, we demonstrate that BCF treatment significantly sup-presses the onset of metastatic growth in the MK-2206 by activating cellular stress pathways. Notably, BCF inhibition was found to be mediated by the activation of CACNA1H, which increased intracellular influx of cal-cium, leading
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br The above data support Bruceine D
2020-08-24
The above data support Bruceine D as being a potential candidate to treat cancer. In the present study, we investigate the cytotoxic effects of BD on NSCLC cell lines in vitro and explore the underlying mechanism of BD in cytotoxicity and apoptosis. 2. Materials and methods 2.1. Chemicals and
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br NP vectors have emerged
2020-08-18
NP vectors have emerged as a promising alternative to viral systems for targeted in vivo delivery of nucleic 56-65-5 therapies. Stable in vivo knockdown using siRNA delivery systems has been achieved and several compounds have received FDA approval44. However, the efficiency of nucleic acid deliv
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br Conclusions br This study expands on
2020-08-18
3. Conclusions This study expands on the discovery of the high efficacy in vitro in a human clear-cell renal carcinoma cell line displayed by bime-tallic titanocene-gold derivatives. One of the compounds (Tita-nocref) had been described as extremely efficacious in vitro and Fig. 7. Heat map
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br Conflict of interest br There
2020-08-18
Conflict of interest There are no conflicts of interests. References Bruneton, J., 1999. Généralités, in: Pharmacognosie, phytochimie, plantes médicinales. Dhamgaye, S., Devaux, F., Vandeputte, P., Khandelwal, N.K., Sanglard, D., Mukhopadhyay, G., Prasad, R., 2014. Molecular mechanisms
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br MODEL br Asian Surgical Association and Taiwan
2020-08-18
+ MODEL ª 2019 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/). 1. Introduction Colorectal cancer (CRC) is the most com
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br and the Malmo Preventive Project
2020-08-18
[2] and the Malmo Preventive Project [15].]FID$T1[Our study differs from these two studies with regards to not only race but also other key factors, including length of follow-up (one decade vs 2+ decades), outcome definition (aggressive vs metastat-ic/fatal disease), time period (pre-PSA vs post-
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Feng Y Huang R He Y et al Efficacy
2020-08-18
33. Feng Y, Huang R, He Y, et al. Efficacy of physical examination, ultrasound, and ultrasound combined with fine-needle aspiration for axilla staging of primary breast cancer. Breast Cancer Res Treat 2015; 149:761-5. 34. Majid S, Tengrup I, Manjer J. Clinical assessment of axillary 2260791-14-6
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br Medication type Statin br Aspirin br
2020-08-18
Medication type Statin Aspirin Characteristic No Yes P-value No Yes P-value Race/ethnicity Obesity Hypertension Diabetes mellitus Hypercholesterolemia Histology Cancer stage Hysterectomy Chemotherapy Cancer recurrence Patient demographics are gro
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br In silico transcription factor binding site prediction br
2020-08-14
3.5. In-silico transcription factor binding site prediction TFBS analysis by PROMO predicted that the presence of minor at both loci results in gain of Pax-5 and p53 binding sites. While AP-2alphaA binding site was lost for rs2276201and for rs9347683 C/ EBPbeta, NF-1 and ENKTF-1 binding sites w