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br Western blot assay br For
2020-07-26
4.4. Western blot assay For Western blot analysis, Cycloheximide were treated with the indicated concentrations of drugs for 24 and 48 h and then harvested by scraping with lysis buffer (1 mM EGTA, 1 mM EDTA, 150 mM NaCl, 1% Triton X-100, 2.5 mM sodium pyrophosphate, 1 mM PMSF, 1 mM Na3VO4,
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Eun CS Kim BK Han DS Kim SY
2020-07-25
[7] Eun CS, Kim BK, Han DS, Kim SY, Kim KM, Choi BY, et al. Differences in gastric mu-cosal microbiota profiling in patients with chronic gastritis, intestinal metaplasia, and gastric cancer using pyrosequencing methods. Helicobacter 2014;19:407–16. [8] Aviles-Jimenez F, Vazquez-Jimenez F, Medrano-
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br Clinically the long infusion time of up
2020-07-08
Clinically, the long infusion time of up to 24 h (slow drug inflow rate) for chemotherapy is recommended to avoid hypersensitivity or allergic reactions caused by the immune system. However, such long hospitalization causes burdens in outpatient administration, increases administration costs, and
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br z Adjusted for variables in b previous history of
2020-03-24
z Adjusted for variables in “b” þ previous history of diabetes (yes, no). x Adjusted for variables in “b” þ waist circumference. k Adjusted for variables in “b” þ waist to hip ratio. Analyses were performed using Stata 14.1 (StataCorp, College Station, TX). All P-values are two-sided. Resu
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br with miR located within the
2020-03-24
with miR-17 located within the miR-17-92 cluster and the miR-106b-25 cluster [11]. It has been reported that an autoregulatory feedback loop between E2F1 and miR20b-5p is involved in cell proliferation and differentiation [12]. However, only a few studies have investigated whether miR20b mediates t
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br Burnside ES Drukker K Li H et
2020-03-24
9. Burnside ES, Drukker K, Li H, et al. Using computer-extracted image phenotypes from tumors on breast magnetic resonance imaging to pre-dict breast cancer pathologic stage. Cancer 2016; 122:748–757. 10. Mazurowski MA, Zhang J, Grimm LJ, et al. Radiogenomic analysis of breast cancer: luminal b
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br Discussion br This study on men
2020-03-24
Discussion This study on 104 men treated for rectal cancer demonstrates that the risk of severe postoperative adverse events is related to radiation-induced primary testicular failure, displayed by preop-erative decrease in T levels and increase in LH/T-ratio. We have previously demonstrated
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br Patients could have received more than of
2020-03-24
‡Patients could have received more than 1 of the specified chemotherapeutic agents. Reference to such patients is patients who did not receive any of the specified chemotherapeutic agents. treated with conventional chemotherapy developed AKI, whereas 74% of the patients with AMLs treated with o
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br Combining BBR with signal transduction inhibitors chemoth
2020-03-24
1.4. Combining BBR with signal transduction inhibitors, chemotherapeutic drugs and other therapeutic agents The drug resistance of various cancer Amiloride HCL can be reversed or reduced by combining BBR with certain signal transduction pathway inhibitors. BBR seems to interact well with EGFR
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br Next we examined the applicability
2019-10-29
Next, we examined the applicability of TAB-3-GSH for targeting tumor in vivo. A nude mouse implanted with subcutaneous xenografts of SKOV-3 cell line at the left posterior axillary was used as the animal model. After intraperitoneal (i.p.) injection of TAB-3-GSH (4 mM, 200 μL), fluorescence signal
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br Wang et al also observed microtubule
2019-10-22
Wang et al. [41] also observed microtubule condensation in the unstructured nuclei of the cells with spindle multipolarization in prostate cancer cells exposed to similar doses of PTX (50 nM). These results not only indicate that NP encapsulation of the drug has no effect on its antimitotic m
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br Fig A In vivo fluorescence images of
2019-10-21
Fig. 6. (A) In vivo fluorescence images of MDA-MB-231 xenograft nude mice after i.v. injection of free DiR and [email protected] NPs. The arrows indicate the tumor foci of mice. (B) Ex vivo distribution and (C) statistical analysis of hearts (H), livers (Li), spleens (S), lungs (Lu), kidneys (K) and
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Cefepime br Table br Computed ApoC values
2019-10-21
Table 3 Computed ApoC50 values for 1 and CDDP according results of Annexin V/PI double staining method after 24 h incubation. Compound ApoC50 [μM] a n.d. - not determined as no activity was observed in the concentration range 1–100 μM. cell cycle distribution of MCF-7 and AsPC-1 cells