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br Patients could have received more than of
2020-03-24
‡Patients could have received more than 1 of the specified chemotherapeutic agents. Reference to such patients is patients who did not receive any of the specified chemotherapeutic agents. treated with conventional chemotherapy developed AKI, whereas 74% of the patients with AMLs treated with o
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br Combining BBR with signal transduction inhibitors chemoth
2020-03-24
1.4. Combining BBR with signal transduction inhibitors, chemotherapeutic drugs and other therapeutic agents The drug resistance of various cancer Amiloride HCL can be reversed or reduced by combining BBR with certain signal transduction pathway inhibitors. BBR seems to interact well with EGFR
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br Next we examined the applicability
2019-10-29
Next, we examined the applicability of TAB-3-GSH for targeting tumor in vivo. A nude mouse implanted with subcutaneous xenografts of SKOV-3 cell line at the left posterior axillary was used as the animal model. After intraperitoneal (i.p.) injection of TAB-3-GSH (4 mM, 200 μL), fluorescence signal
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br Wang et al also observed microtubule
2019-10-22
Wang et al. [41] also observed microtubule condensation in the unstructured nuclei of the cells with spindle multipolarization in prostate cancer cells exposed to similar doses of PTX (50 nM). These results not only indicate that NP encapsulation of the drug has no effect on its antimitotic m
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br Fig A In vivo fluorescence images of
2019-10-21
Fig. 6. (A) In vivo fluorescence images of MDA-MB-231 xenograft nude mice after i.v. injection of free DiR and [email protected] NPs. The arrows indicate the tumor foci of mice. (B) Ex vivo distribution and (C) statistical analysis of hearts (H), livers (Li), spleens (S), lungs (Lu), kidneys (K) and
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Cefepime br Table br Computed ApoC values
2019-10-21
Table 3 Computed ApoC50 values for 1 and CDDP according results of Annexin V/PI double staining method after 24 h incubation. Compound ApoC50 [μM] a n.d. - not determined as no activity was observed in the concentration range 1–100 μM. cell cycle distribution of MCF-7 and AsPC-1 cells